Recent pubilications:                            more

Chen Q#*, Yan M#, Cao Z#, Li X#, Zhang Y#, Shi J#, Feng GH, Peng H, Zhang X,Zhang Y, Qian J, Duan E*, Zhai Q*, Zhou Q*. (2016) Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder. Science 351(6271):397-400.

Li X#, Cui XL#, Wang JQ#, Wang YK, Li YF, Wang LY, Wan HF, Li TD, Feng GH, Shuai L, Li ZK, Gu Q, Hao J, Wang L, Zhao XY, Liu ZH, Wang XJ, Li W*, Zhou Q*. (2016) Generation and application of mouse-rat allodiploid embryonic stem cells. Cell 164(1-2):279–292.


Recent Progress:                                   more

From subtlety to fate: new insights for the first mammalian embryo fate decision In mammalian preimplantation embryo development, when the first asymmetry emerges and how it develops to direct distinct cell fates are two longstanding questions. It remains debatable whether the first bifurcation of cell fate emerges randomly at morula stage, or has been predetermined at earlie......

2014-11-17 首页小图.jpg
Water Channel-dependent excessive uterinefluid impairs embryo implantation In mammalian species, embryo implantation is the threshold for pregnancy establishment, the abnormality of which accounts for ~75% of human pregnancy loss. Abnormal preimplantation hormonal environment is a common cause for defective embryo implantation, usually attributed to the changed endometr......

2014-06-30 段恩奎 小图1.jpg
Embryo-uterine orientation at implantation requires uterine RBPJ signaling Rodent blastocysts show remarkably consistent embryonic orientation with respect to the uterine structure, an orientation established at initial implantation which blueprints the direction of future embryo-uterine axis. However, despite this interesting phenomenon having been discovered more than......

Integrative Proteomic and Transcriptomic Analyses Reveal Multiple Post-transcriptional Regulatory Mechanisms of Mouse Spermatogenesis Dr.Chunsheng Han’s group in SKLRB collaborated with Dr. Fuquan Yang’s team in the Key Laboratory of Protein and Peptide Pharmaceuticals & Laboratory of Proteomics, Institute of Biophysics, CAS in examining protein expression during mouse spermatogenesis using iTRAQ technology—an up-to-date hig......

Recent News                                     more

The first debate competition is preparing The state key laboratory of reproductive biology will hold the first session of debate competition. The title of the competition is “If sperm is more important than oocyte?” The leader of the district side is Wei Li and the a......

The first ‘Voice Of Science’ forum of SKLRB graduate students The ‘Voice Of Science’ forum is the annual science communication party in SKLRB. This forum is to not only pick out the annual trump card from the graduate students, but also improve the scientific spark collision among all t......

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National Population and Family Planning Commission of P.R.China
State Key Laboratory of Reproductive Medicine