Achievements--State Key Laboratory of Stem Cell and Reproductive Biology (SRLab)

1. Yu L, Li D, Liao QP, Yang HX, Cao B, Fu G, Ye G, Bai Y, Wang H, Cui N, Liu M, Li YX, Li J, Peng C, Wang YL: High levels of activin a detected in preeclamptic placenta induce trophoblast cell apoptosis by promoting nodal signaling. J Clin Endocrinol Metab 97(8):E1370, 2012.
2. Fu YY, Nergard JC, Barnette NK, Wang YL, Chai KX, Chen LM: Proteasome Inhibition Augments Cigarette Smoke-Induced GM-CSF Expression in Trophoblast Cells via the Epidermal Growth Factor Receptor. PLoS One 7(8):e43042, 2012.
3. Yang Y, Wang Y, Zeng X, Ma XJ, Zhao Y, Qiao J, Cao B, Li YX, Ji L, Wang YL: Self-Control of HGF Regulation on Human Trophoblast Cell Invasion via Enhancing c-Met Receptor Shedding by ADAM10 and ADAM17. J Clin Endocrinol Metab 97(8):E1390, 2012.
4. Gu Q, Hao J, Zhao XY, Li W, Liu L, Wang L, Liu ZH, Zhou Q: Rapid conversion of human ESCs into mouse ESC-like pluripotent state by optimizing culture conditions. Protein Cell 3(1):71, 2012.
5. Bai Y, Yang W, Yang HX, Liao Q, Ye G, Fu G, Ji L, Xu P, Wang H, Li YX, Peng C, Wang YL: Downregulated miR-195 detected in preeclamptic placenta affects trophoblast cell invasion via modulating ActRIIA expression. PLoS One 7(6):e38875, 2012.
6. Chao SB, Guo L, Ou XH, Luo SM, Wang ZB, Schatten H, Gao GL, Sun QY: Heated spermatozoa: effects on embryonic development and epigenetics. Hum Reprod 27(4):1016, 2012.
7. Hu HM, Zhang SB, Lei XH, Deng ZL, Guo WX, Qiu ZF, Liu S, Wang XY, Zhang H, Duan EK: Estrogen Leads to Reversible Hair Cycle Retardation through Inducing Premature Catagen and Maintaining Telogen. PLoS One 7(7):e40124, 2012.
8. Zhang QH, Qi ST, Wang ZB, Yang CR, Wei YC, Chen L, Ouyang YC, Hou Y, Schatten H, Sun QY: Localization and function of the Ska complex during mouse oocyte meiotic maturation. Cell Cycle 11(5):909, 2012.
9. Lu C, Lin L, Tan H, Wu H, Sherman SL, Gao F, Jin P, Chen D: Fragile X Premutation RNA is Sufficient to Cause Primary Ovarian Insufficiency in Mice. Hum Mol Genet, 2012.
10. Guo L, Qi ST, Miao DQ, Liang XW, Li H, Ou XH, Huang X, Yang CR, Ouyang YC, Hou Y, Sun QY, Han Z: The Roles of Parathyroid Hormone-Like Hormone during Mouse Preimplantation Embryonic Development. PLoS One 7(7):e40528, 2012.
11. Lin HY, Underhill C, Lei JH, Helander-Claesson A, Lee HY, Gardill BR, Muller YA, Wang H, Hammond GL: High frequency of SERPINA6 polymorphisms that reduce plasma corticosteroid-binding globulin activity in Chinese subjects. J Clin Endocrinol Metab 97(4):E678, 2012.
12. Gao WL, Liu M, Yang Y, Yang H, Liao Q, Bai Y, Li YX, Li D, Peng C, Wang YL: The imprinted H19 gene regulates human placental trophoblast cell proliferation via encoding miR-675 that targets Nodal Modulator 1 (NOMO1). RNA Biol 9(7), 2012.
13. Hu MW, Wang ZB, Schatten H, Sun QY: New understandings on folliculogenesis/oogenesis regulation in mouse as revealed by conditional knockout. J Genet Genomics 39(2):61, 2012.
14. Li S, Ou XH, Wei L, Wang ZB, Zhang QH, Ouyang YC, Hou Y, Schatten H, Sun QY: Septin 7 is required for orderly meiosis in mouse oocytes. Cell Cycle 11(17), 2012.
15. Xia L, Zheng X, Zheng W, Zhang G, Wang H, Tao Y, Chen D: The niche-dependent feedback loop generates a BMP activity gradient to determine the germline stem cell fate. Curr Biol 22(6):515, 2012.
16. Liu ZK, Liu HY, Fang WN, Yang Y, Wang HM, Peng JP: Insulin-like growth factor binding protein 7 modulates estrogen-induced trophoblast proliferation and invasion in HTR-8 and JEG-3 cells. Cell Biochem Biophys 63(1):73, 2012.
17. Ma JY, Liang XW, Schatten H, Sun QY: Active DNA demethylation in mammalian preimplantation embryos: new insights and new perspectives. Mol Hum Reprod 18(7):333, 2012.
18. Guo CL, Han FF, Wang HY, Wang L: Meta-analysis of the association between hOGG1 Ser326Cys polymorphism and risk of colorectal cancer based on case-control studies. J Cancer Res Clin Oncol 138(9):1443, 2012.
19. Chen L, Chao SB, Wang ZB, Qi ST, Zhu XL, Yang SW, Yang CR, Zhang QH, Ouyang YC, Hou Y, Schatten H, Sun QY: Checkpoint kinase 1 is essential for meiotic cell cycle regulation in mouse oocytes. Cell Cycle 11(10):1948, 2012.
20. Ou XH, Li S, Wang ZB, Li M, Quan S, Xing F, Guo L, Chao SB, Chen Z, Liang XW, Hou Y, Schatten H, Sun QY: Maternal insulin resistance causes oxidative stress and mitochondrial dysfunction in mouse oocytes. Hum Reprod 27(7):2130, 2012.
21. Sheng C, Zheng Q, Wu J, Xu Z, Wang L, Li W, Zhang H, Zhao XY, Liu L, Wang Z, Guo C, Wu HJ, Liu Z, Wang L, He S, Wang XJ, Chen Z, Zhou Q: Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factors. Cell Res 22(1):208, 2012.
22. Zhao KQ, Lin HY, Zhu C, Yang X, Wang H: Maternal Smad3 deficiency compromises decidualization in mice. J Cell Biochem 113(10):3266, 2012.
23. Liu Z, Hai T, Dai X, Zhao X, Wang Y, Brochard V, Zhou S, Wan H, Zhang H, Wang L, Zhou Q, Beaujean N: Early patterning of cloned mouse embryos contributes to post-implantation development. Dev Biol 368(2):304, 2012.
24. Guo CL, Liu L, Jia YD, Zhao XY, Zhou Q, Wang L: A novel variant of Oct3/4 gene in mouse embryonic stem cells. Stem Cell Res 9(2):69, 2012.
25. Wu L, Zhou H, Lin H, Qi J, Zhu C, Gao Z, Wang H: Circulating microRNAs are elevated in plasma from severe preeclamptic pregnancies. Reproduction 143(3):389, 2012.
26. Ma JY, Li M, Ge ZJ, Luo Y, Ou XH, Song S, Tian D, Yang J, Zhang B, Ou-Yang YC, Hou Y, Liu Z, Schatten H, Sun QY: Whole transcriptome analysis of the effects of type I diabetes on mouse oocytes. PLoS One 7(7):e41981, 2012.