Achievements--State Key Laboratory of Stem Cell and Reproductive Biology (SRLab)

Peng Xu, Yangyu Zhao, Ming Liu, Yongqing Wang, Hao Wang, Yu-xia Li, Xiaoming Zhu, Yuanqing Yao, Haibin Wang, Jie Qiao, Lei Ji,* Yan-ling Wang*, variations of micrornas in human placentas and plasma from preeclamptic pregnancy. Hypertension, 2014 Jun;63(6):1276-1284 (IF=6.873)
Min Chen, Xiaona Wang, Yanbo Wang, Lianjun Zhang, Binyang Xu, Limin Lv, Xiuhong Cui, Wei Li,and Fei Gao* wt1 is involved in leydig cell steroid hormone biosynthesis by regulating paracrine. Biol Reprod, 2014 Apr 3, 90(4):71. (IF=4.027)
Wang R#, Dang YL#, Zheng R, Li Y, Li WW, Lu XY, Wang LJ, Zhu C, Lin HY*, Wang H*. Live cell imaging of in vitro human trophoblast syncytialization. Biol Reprod, 2014 Jun, 90(6):117 (cover story). (IF=4.027)
Chang WL, Yang Q, Zhang H, Lin HY, Zhou Z, Lu X, Zhu C, Xue LQ, Wang H*, Role of placenta-specific protein 1 in trophoblast invasion and migration. Reproduction. 2014 Oct;148(4):343-352 (IF=3.555)
Xuepeng Wang1, Yan Yuan1, Quan Zhou, Haifeng Wan, Mei Wang, Qi Zhou, Xiao-Yang Zhao*,Jiahao Sha,* rna guided genome editing in mouse germ-line stem cells. Journal of Genetics and Genomics (JGG/Letter to the Editor) , 2014 Jul 20;41(7):409-411 (IF=2.076)
Song Wang, Wei Li, Shuo Wang, Baoyang Hu, rapid and efficient assembly of transcription activator-like effector genes by user cloning. Journal of Genetics and Genomics. 2014 Jun 20, 41(6):339-347 (IF=2.076)
Zhang LinLin & Zhou Qi,* CRISPR/Cas technology: a revolutionary approach for genome engineering. Science China(Life Sciences), 2014 Jun;57(6):639-640 (IF=1.502)
Lu Wang,1,3,9 Jun Zhang,4,9 Jialei Duan,1,9 Xinxing Gao,4,9 Wei Zhu,1,3 Xingyu Lu,5 Lu Yang,6 Jing Zhang,1 Guoqiang Li,1,3 Weimin Ci,2 Wei Li,7 Qi Zhou,7 Neel Aluru,8 Fuchou Tang,6 Chuan He,5 Xingxu Huang,4,* and Jiang Liu1,* Programming and Inheritance of Parental DNA Methylomes in Mammals Cell 157, 979–991, May 8, 2014（IF=31.957）
K Liu1,2,4, Y Song1,4, H Yu1,3,4 and T Zhao*1 Understanding the roadmaps to induced pluripotency Cell Death and Disease（ Review）2014, 5, e1232; doi:10.1038/cddis.2014.205（IF=6.044）
Ge ZJ, Zhang CL, Schatten H, Sun QY. Maternal Diabetes Mellitus and the Origin of Non-Communicable Diseases in Offspring: The Role of Epigenetics. Biol Reprod. 2014 May 14. pii: biolreprod.114.118141. [Epub ahead of print] （IF=4.027）
Hu MW, Wang Zb, Jaing ZZ, Qi ST, Huang L, Liang QX, Schatten H, Sun QY. Scaffold Subunit Aalpha of PP2A Is Essential for Female Meiosis and Fertility Biol Reprod. 2014, June 4. doi:10.1095/biolreprod.114.120220 （IF=4.027）
Hai-Yan Liu,1,2 Zhen-Kun Liu,1 Huhe Chao,1,2 Zhongyin Li,1,2 Zhihui Song,1,2 Ying Yang,1 and Jing-Pian Peng1 High-dose interferon-γ promotes abortion in mice by suppressing treg and th17 polarization Journal of Interferon & Cytokine Research 2014,34(5):394-403 （IF=3.297）
Yuran Song1,2, Tang Hai1, Ying Wang1, Runfa Guo1, Wei Li1, Liu Wang1, Qi Zhou1 Epigenetic reprogramming, gene expression and in vitro development of porcine SCNT embryos are significantly improved by a histone deacetylase inhibitor—m-carboxycinnamic acid bishydroxamide (CBHA) Protein Cell 2014, 5(5):382–393 DOI 10.1007/s13238-014-0034-3 （IF=3.22）
Qi Gu1,3, Jie Hao1, Tang Hai1, Jianyu Wang1,2, Yundan Jia1, Qingran Kong2, Juan Wang1,2, Chunjing Feng1, Binghua Xue2, Bingteng Xie2, Shichao Liu2, inyu Li2, Yilong He2, Jialu Sun2, Lei Liu1, Liu Wang1, Zhonghua Liu2&, Qi Zhou1 Efficient generation of mouse ESCs-like pig induced pluripotent stem cells. Protein Cell（LETTER）2014, 5(5):338–342（IF=3.22）
Zhang Y1, Zhang Y1, Shi J1, Zhang H, Cao Z, Gao X, Ren W, Ning Y, Ning L, Cao Y, Chen Y, Ji W, Chen ZJ*, Chen Q*, Duan E*. Identification and characterization of an ancient class of small RNAs enriched in serum associating with active infection. J Mol Cell Biol. 2014 Apr;6(2):172-174. (IF=7.308) (Editor's recommendation) (Cover Story)
Long Yan1, Weixiao Liu1, Huihui Zhang2, Chao Liu1, Yongliang Shang1, Yihong Ye3, Xiaodong Zhang2,* and Wei Li1*. Ube2g2–gp78-mediated HERP polyubiquitylation is involved in ER stress recovery. Journal of Cell Science (IF=5.877) 2014,127:1417-1427 doi:10.1242/jcs.135293
Xinyue Wang, Shu Liu, Qian Zhao, Na Li, Huishan Zhang, Xudong Zhang, Xiaohua Lei, Huashan Zhao, Zhili Deng, Jingqiao Qiao, Yujing Cao, Lina Ning, Shuang Liu*, Enkui Duan*. Three-dimensional hydrogel scaffolds facilitate in vitro self-renewal of human skin-derived precursors,. Acta Biomaterialia, (IF=5.093) Available online 28 March 2014, ISSN 1742-7061, http://dx.doi.org/10.1016/j.actbio.2014.03.018.
Hai T, Teng F, Guo RF, Li W, Zhou Q*. One-step generation of knockout pigs by zygote injection of CRISPR/Cas system. Cell Research 2014.11.doi: 10.1038/cr. (IF=10.526)
Shanming Ji*, Ming Sun*, Xiudeng Zheng*, Lin Li, Liwei Sun, Dahua Chen, Qinmiao Sun Cell-surface localization of Pellino antagonizes Toll-mediated innate immune signalling by controlling MyD88 turnover in Drosophila. Nat Commun Published 17 Mar 2014/DOI: 10.1038//ncomms4458 （IF=10.015）
Peng Xu,* Yangyu Zhao,* Ming Liu, Yongqing Wang, Hao Wang, Yu-xia Li, Xiaoming Zhu, Yuanqing Yao, Haibin Wang, Jie Qiao, Lei Ji,* Yan-ling Wang* Variations of micrornas in human placentas and plasma from preeclamptic pregnancy. Hypertension 2014, March 24 online ISSN: 1524-4563（IF=6.873）
Jiang ZZ, Hu MW, Wang ZB, Huang L, Lin F, Qi ST, Ouyang YC, Fan HY, Schatten H, Mak TW, Sun QY* Survivin is essential for fertile egg production and female fertility in mice. Cell Death Dis. 2014 Mar 27;5:e1154. doi: 10.1038/ cddis. 2014.126.(IF=6.044)
Hai-Yan Liu, Huhe Chao, Zhen-Kun Liu, Hong-Fei Xia, Zhihui Song, Ying Yang, Jing-Pian Peng,* Regulation of cyp26a1 on Th17 cells in mouse peri-implantation. J. Cell. Mol. Med. 2014,18(3):455-467 (IF=4.753)
Jianxiu Hao, Min Chen, Shaoyang Ji, Xiaona Wang, Yanbo Wang, Xingxu Huang, Lin Yang, Yaqing Wang, Xiuhong Cui, Limin Lv, Yixun Liu, Fei Gao* Equatorin is not essential for acrosome biogenesis but is required for the acrosome reaction. Biochem Bioph Res Co 2014,444:537–542 (IF=2.406)
Gengzhen Zhu, Yujing Li, Fei Zhu, Tao Wang, Wensong Jin, Wei Mu, Wei Lin, Weiqi Tan, Wenqi Li, R. Craig Street, Siying Peng, Jian Zhang, Yue Feng, Stephen T. Warren, Qinmiao Sun,* Peng Jin,* Dahua Chen Coordination of Engineered Factors with TET1/2 Promotes Early-Stage Epigenetic Modification during Somatic Cell Reprogramming. Stem Cell Reports 2014, 2: 253–261(March 11)
Weixiao Liu, Yongliang Shang, Yan Zeng, Chao Liu, Yanchang Li, Linhui Zhai, Pan Wang, Jizhong Lou, Ping Xu, Yihong Ye, & Wei Li*, Dimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chains. The EMBO Journal. 2014,33(1):46-61(IF=9.822)
Wei Y, Yang CR, Wei YP, Zhao ZA, Hou Y, Schatten H, Sun QY*, Paternally induced transgenerational inheritance of susceptibility to diabetes in mammals. Proc Natl Acad Sci U S A. 2014 Feb 4; 111(5):1873-1878. (IF=9.737)
Ge ZJ, Luo SM, Lin F, Liang QX, Huang L, Wei YC, Hou Y, Han ZM, Schatten H, Sun *. DNA methylation in oocytes and liver of female mice and their offspring: effects of high-fat-diet-induced obesity. Environ Health Perspect. 2014 Feb; 122(2):159-64. (IF=7.26)
W Li, D Liu, W Chang, X Lu, Y-L Wang, H Wang, C Zhu, H-Y Lin, Y Zhang, J Zhou*, and H Wang*, Role of IGF2BP3 in trophoblast cell invasion and Migration. Cell Death and Disease. 2014, 5, e1025; doi:10.1038/cddis.2013.545(IF=6.044)
Yu C, Zhang YL, Pan WW, Li XM, Wang ZW, Ge ZJ, Zhou JJ, Cang Y, Tong C, Sun QY*, Fan HY*. CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins. Science. 2013 Dec 20; 342(6165):1518-21. doi: 10.1126/science.1244587. (IF=31.027)
Weixiao Liu, Yongliang Shang, Yan Zeng, Chao Liu, Yanchang Li, Linhui Zhai, Pan Wang, Jizhong Lou, Ping Xu, Yihong Ye,** & Wei Li,*。Dimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chains. The EMBO Journal, 2014, 33(1):46-61 (IF=9.822)
Wei Y, Yang CR, Wei YP, Zhao ZA, Hou Y, Schatten H, Sun QY*. Paternally induced transgenerational inheritance of susceptibility to diabetes in mammals. Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1873-1878. (IF=9.737)
Ge ZJ, Luo SM, Lin F, Liang QX, Huang L, Wei YC, Hou Y, Han ZM, Schatten H, SunQY *. DNA methylation in oocytes and liver of female mice and their offspring: effects of high-fat-diet-induced obesity. Environ Health Perspect. 2014 Feb; 122(2):159-64. (IF=7.26)