1. Epigenetic Programming and Reprogramming during Development
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Yan et al. Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development. Nat Genet (2023)
PMID: 36539615
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Yan et al. Decoding dynamic epigenetic landscapes in human oocytes using single-cell multi-omics sequencing. Cell Stem Cell (2021)
PMID: 33957080
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Gu et al. Integrative single-cell analysis of transcriptome, DNA methylome and chromatin accessibility in mouse oocytes. Cell Res (2019)
PMID: 30560925
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Li et al. Single-cell multi-omics sequencing of human early embryos. Nat Cell Biol (2018)
PMID: 29915357
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Guo et al. Single-cell multi-omics sequencing of mouse early embryos and embryonic stem cells. Cell Res (2017)
PMID: 28621329
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Guo et al. The transcriptome and DNA methylome landscapes of human primordial germ cells. Cell (2015)
PMID: 26046443
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Guo et al. Active and passive demethylation of male and female pronuclear DNA in the mammalian zygote. Cell Stem Cell (2014)
PMID: 25220291
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Gu et al. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature (2011)
PMID: 21892189
2. Epigenetic Regulation in Cell Fate Determination and Transition
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Chen et al. Integration of single-cell transcriptome and chromatin accessibility of early gonads development among goats, pigs, macaques, and humans. Cell Rep (2022)
PMID: 36323261
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Yang et al. Chemical pretreatment activated a plastic state amenable to direct lineage reprogramming. Front Cell Dev Biol (2022)
PMID: 35399519
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Yang et al. Chemicals orchestrate reprogramming with hierarchical activation of master transcription factors primed by endogenous Sox17 activation. Commun Biol (2020)
PMID: 33128002
3. Epigenetics in Disease Evolution and Development
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Zhang et al. Single-cell sequencing identifies differentiation-related markers for molecular classification and recurrence prediction of PitNET. Cell Rep Med (2023)
PMID: 36754052
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Long et al. Obesity modulates cell-cell interactions during ovarian folliculogenesis. iScience (2022)
PMID: 35005562
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Shen et al. Unveiling the heterogeneity of NKT cells in the liver through single cell RNA sequencing. Sci Rep (2020)
PMID: 33173202
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Chen et al. Med23 serves as a gatekeeper of the myeloid potential of hematopoietic stem cells. Nat Commun (2018)
PMID: 30218073
4. Novel Molecular and Cell Biology Techniques
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Wu et al. An aggregation of human embryonic and trophoblast stem cells reveals the role of trophectoderm on epiblast differentiation. Cell Prolif (2023)
PMID: 37199067
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Zhai et al. Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture. Cell (2023)
PMID: 37172562
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Qian et al. lsolation of mouse ovarian follicles for single-cell RNA-seq and in vitro culture. STAR Protoc (2022)
PMID: 35830306
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Yan et al. Protocol for scChaRM-seq: Simultaneous profiling of gene expression, DNA methylation, and chromatin accessibility in single cells. STAR Protoc (2021)
PMID: 34849489
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Zhou et al. Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis. Nature (2019)
PMID: 31181567
5. Cell Atlas and Knowledge Bases
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Yan et al. The longitudinal single-cell panorama of cynomolgus monkey ovary throughout lifespan revealed a conserved ovarian clock between primates. bioRxiv (2023)
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Zhai et al. Primate gastrulation and early organogenesis at single-cell resolution. Nature (2022)
PMID: 36517595